WordPress.com have announced Custom Design an upgrade that can make your blog look and feel exactly the way you want.
“Easily customize the fonts in your theme with fonts from Typekit, and dive into CSS (Cascading Stylesheet) to make all the presentational changes you desire.”
Custom Design is a paid upgrade that costs $30.00 per blog, per year.
The Custom Design upgrade replaces the Custom CSS and Typekit fonts upgrades
Read more: http://en.support.wordpress.com/custom-design/